Prediction: These 4 Stocks Will 4x in the Next 10 Years

Many investors probably aren't in the mood to buy stocks right now. September is typically the worst month for stocks, and rising interest rates are driving more investors toward the safety of CDs, T-bills, and other fixed-income investments.

But as the bulls look the other way, investors who can stomach the near-term volatility should still consider nibbling on some stocks with tremendous long-term growth potential. I believe these four stocks -- Opendoor (NASDAQ: OPEN), NIO (NYSE: NIO), Bloom Energy (NYSE: BE), and Strategy (NASDAQ: MSTR) -- could quadruple within the next four years.

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Opendoor

Opendoor, the largest instant homebuyer (iBuyer) in the U.S., uses AI algorithms to make cash offers on homes. It then fixes up those properties and relists them on its own marketplace. That business model thrives when interest rates are low and the housing market is hot, but it faces formidable challenges when interest rates rise and the housing market cools off.

That's why Opendoor's stock now trades at just 0.3 times next year's sales and 93% below its all-time high. But at these bargain-bin valuations, much of the bad news is already priced into the stock. The Fed's recent interest rate hike suggests it will remain under pressure. However, if interest rates drop and the housing market recovers over the next decade, Opendoor's stock could easily quadruple and still be considered a bargain.

NIO

Nio, a major producer of electric vehicles (EVs) in China and Europe, trades at just 0.4 times next year's sales and 94% below its all-time high. But NIO isn't a small and speculative EV maker. It produces a wide range of electric sedans and SUVs, and it delivered 326,028 vehicles in 2025. Its vehicles are equipped with removable batteries that can be swapped out at its battery-swapping stations as a faster alternative to conventional chargers.

Nio's stock tumbled amid concerns regarding the costly expansion of its battery-swapping network and the production of its own first-party automotive chips. Intense competition also limited its pricing power and compressed its margins. However, NIO finally turned profitable on an adjusted basis in the first half of 2026, and its stock could soar if more investors value it like Tesla (NASDAQ: TSLA) -- which trades at 12 times next year's sales.

Bloom Energy

Bloom Energy develops solid oxide fuel cells (SOFCs), which can convert natural gas, biogas, hydrogen, propane, and hydrogen into electricity without any combustion. Its SOFC systems can also be deployed in less than two months, while conventional grid-based connections can take years to set up. Those advantages make them a popular choice for data center operators, who use these SOFC systems to satisfy the AI market's surging electricity demand.

Bloom's backlog swelled to $20 billion at the end of 2025. That's roughly ten times the $2.0 billion in revenue it generated in 2025. Bloom's stock has already soared 2,700% over the past two years as the AI market expanded, but it still doesn't seem overvalued at 12 times this year's sales. It could soar much higher as it converts more of its backlog into actual revenue.

Strategy

Strategy, the world's largest corporate holder of Bitcoin (CRYPTO: BTC), holds 846,000 Bitcoins. Those holdings are worth $70.6 billion today, compared to its market cap of $66.3 billion. Strategy trades at a discount to the net asset value (NAV) of its Bitcoin holdings because investors are concerned about its reliance on stock and debt offerings to fund those purchases. Strategy also occasionally sells some of its Bitcoin to fund its preferred stock dividends.

However, Bitcoin's price has risen nearly 40% to about $83,000 over the past three months. Strategy's executive chairman, Michael Saylor, believes its price could hit $21 million by 2046. If that happens, Strategy's stock could deliver big multibagger gains over the next decade.

Leo Sun has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Bitcoin, Bloom Energy, and Tesla. The Motley Fool has a disclosure policy.