Oklo recently acquired Atomic Alchemy, which will expand the company's capabilities beyond selling SMRs.
As the second-largest uranium miner, Cameco is the force fueling the nuclear industry recovery.
Nuclear energy is needed to meet the ever-growing power demand of AI and data centers.
The electricity demand from artificial intelligence has created an immense power problem, and nuclear has emerged as one of the best solutions. Hyperscalers need constant, carbon-free electricity to run their data centers. Nuclear developers and providers are now some of the most important AI infrastructure stocks. Here are four companies positioned to be leaders in the AI power boom through 2027 and beyond.
One of the most talked-about pure-play small modular reactor (SMR) developers is Oklo (NYSE: OKLO). The company, while technically still pre-revenue, has many agreements in the pipeline. They include a 1.2-gigawatt (GW) system for Meta Platforms in Ohio. Oklo also acquired the radioisotope producer Atomic Alchemy to expand its capabilities beyond selling SMRs.
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Oklo skyrocketed in 2025 on enthusiasm for SMRs and nuclear's role within the AI renaissance. It has since pulled back dramatically. Oklo's stock has slipped more than 35% over the past 12 months, creating a more appealing entry point for opportunistic yet patient investors.
The company isn't expected to produce significant revenue until the end of 2027 or 2028. Oklo has promising technology, but it remains largely unproven and requires full approval from the Nuclear Regulatory Commission (NRC). Once that hurdle is cleared, the sky is the limit for Oklo.
This stock is best suited for investors with higher risk tolerances and an appetite for near- and intermediate-term volatility.
On the opposite end of the risk spectrum is Constellation Energy (NASDAQ: CEG), which is already the largest owner and operator of nuclear generation in the U.S. The company has long-term power purchase agreements in place with hyperscalers such as Meta and Microsoft.
Constellation also acquired Calpine earlier this year for $26.6 billion. This move doubled Constellation's footprint to approximately 55 GWs. This further positions the company to capture AI-related demand.
Image source: Getty Images.
Constellation does trade at a premium, but that's because it's very much a leader in the nuclear sector and will be for years to come. Constellation is also far less of a risk compared to smaller businesses such as Oklo. It's suited for income and growth investors alike, as it pays $1.70 per share annually. It's not a high-yielding stock, but it is consistently growing its dividend.
Vistra (NYSE: VST) also has long-term power purchase agreements with hyperscalers and a diversified business that operates in nuclear, natural gas, and retail electricity. Vistra's second-quarter results missed analysts' expectations, but the company still posted 30% growth in Ongoing Operations Adjusted EBITDA compared with the prior year. The company also reaffirmed its guidance for the fiscal year.
Vistra plans to acquire Cogentrix by the end of the year, thereby substantially expanding its natural gas fleet. The acquisition recently received approval from the Federal Energy Regulatory Commission.
Vistra's stock has fallen more than 25% over the past 12 months, but the company pays a reasonable quarterly dividend of $0.23 per share. The company's expanding footprint and reasonable price make it a solid buy in the energy sector.
Cameco (NYSE: CCJ) plays an interesting role in the nuclear industry by supplying uranium to these companies. The Canada-based business has long-term contracts to deliver about 230 million pounds of uranium through 2030. It also holds a 49% stake in Westinghouse, a reactor-services giant.
Cameco is fundamentally strong and the second-largest uranium miner in the world, having mined 15% of all uranium in 2025. Momentum behind the stock has pushed it to an incredibly high valuation; however, the company missed expectations in its most recent quarter. Still, Cameco is trading at a premium, and investors should have a longer time horizon to reap the benefits of sustained high nuclear demand.
Cameco pays a modest dividend of about $0.18 per share in U.S. dollars. As far as the nuclear renaissance goes, Cameco isn't as exciting a growth prospect as some of the others, but its role in the industry is crucial.
These four companies are right where they need to be to take advantage of AI's insatiable power needs. Nuclear has to play a significant part in meeting energy demand, and each of these companies plays a different but crucially important role. While Oklo is the most speculative of the four, each has upside potential and many reasons for long-term investors to be optimistic.
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Catie Hogan has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Cameco, Constellation Energy, Meta Platforms, Microsoft, and Vistra. The Motley Fool has a disclosure policy.