3 Monster Stocks to Hold for the Next 10 Years

Source The Motley Fool

Key Points

  • These players sell market-leading products and are tackling growth industries.

  • Holding for several years, rather than a short period, allows investors to fully benefit from each company’s story.

  • These 10 stocks could mint the next wave of millionaires ›

What's a monster stock? It's a well-established company that's demonstrated its strengths over time. You can count on this player for its portfolio of products and its ability to bring in revenue quarter after quarter. The healthcare industry is a great place to look for such investments. Here, you'll find many companies that have been around for years, selling blockbuster drugs and leading medical devices, for example.

These stocks may not deliver huge gains over a short period of time, but over a decade, they could help you generate a significant win. And these are exactly the sorts of building blocks that make a great portfolio. It's important to remember that, in investing, you'll increase your chances of success by holding onto stocks for the long term -- by this I mean at least five years. But 10 years is even better, as it offers the company the opportunity to grow -- and this period may also reduce the impact of any downturns along the way.

Where to invest $1,000 right now? Our analyst team just revealed what they believe are the 10 best stocks to buy right now, when you join Stock Advisor. See the stocks »

Let's check out three monster stocks to hold for the next ten years.

An investor, seen from behind, cheers while looking at something on a smartphone.

Image source: Getty Images.

1. Eli Lilly

Eli Lilly (NYSE: LLY) has been at the center of attention in recent times. This is because the company is leading in one of the highest-growth areas in healthcare: the weight loss drug market, one on track to reach nearly $100 billion by the end of the decade. Lilly's Mounjaro and Zepbound have been generating blockbuster revenue, together surpassing $12 billion in the recent quarter, and driving growth at the pharma giant -- and this is likely to continue.

Lilly recently won approval for Foundayo, a weight loss pill, has a promising candidate in late-stage trials, and is working on other candidates too. Since demand is high in this market, Lilly is wise to make this portfolio a priority.

The company also sells a variety of other drugs across treatment areas and has a long history of earnings growth. So, with Lilly, you gain the stability often found in healthcare companies, along with the weight loss drug growth opportunity that should continue to bear fruit in the years to come.

2 AbbVie

When AbbVie's (NYSE: ABBV) mega-blockbuster Humira headed toward patent expiration, investors worried. After all, the drug at its peak in 2022 brought in more than $21 billion in sales.

But AbbVie prepared for this moment with the development of newer immunology drugs Skyrizi and Rinvoq, and these products are now driving a new era of growth at the company. In the recent quarter, Skyrizi and Rinvoq delivered double-digit increases in revenue to levels of more than $4 billion and $2 billion, respectively. So, it's clear AbbVie has what it takes to surmount the Humira patent expiry.

The company also has a broad portfolio of star products in other indications, from Botox, used in neuroscience and aesthetics, to Vraylar, a treatment for bipolar disorder.

Expansion of indications for its major immunology drugs, as well as a solid pipeline, offer further reasons for optimism -- and to hold onto this pharma stock for the coming decade.

3. Abbott Laboratories

I like Abbott Laboratories (NYSE: ABT) for the company's diversification, something that could make it resilient during challenging times. Abbott includes four business units: medical devices, diagnostics, nutrition, and established pharmaceuticals. If one of these areas faces a headwind, another business may compensate. For example, in later pandemic days, Abbott's coronavirus test sales dropped, while medical device sales picked up momentum.

Abbott also is the name behind leading products and brands, such as the FreeStyle Libre continuous glucose monitor and the Ensure nutrition drink. And the company continues to innovate, winning the regulatory nod for new products -- it recently earned clearance for its next-generation Ultreon artificial intelligence-powered coronary imaging platform. And the company recently completed its acquisition of Exact Sciences, a move that offers it leadership in the oncology diagnostics market.

All of this positions Abbott well for long-term gains, making it a fantastic healthcare stock to buy now and hang onto as this story unfolds.

Where to invest $1,000 right now

When our analyst team has a stock tip, it can pay to listen. After all, Stock Advisor’s total average return is 936%* — a market-crushing outperformance compared to 209% for the S&P 500.

They just revealed what they believe are the 10 best stocks for investors to buy right now, available when you join Stock Advisor.

See the stocks »

*Stock Advisor returns as of June 23, 2026.

Adria Cimino has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends AbbVie, Abbott Laboratories, and Eli Lilly. The Motley Fool has a disclosure policy.

Disclaimer: For information purposes only. Past performance is not indicative of future results.
placeholder
Bitcoin CME gaps at $35,000, $27,000 and $21,000, which one gets filled first?Prioritize filling the $27,000 gap and even try higher.
Author  FXStreet
Aug 22, 2023
Prioritize filling the $27,000 gap and even try higher.
placeholder
Pinduoduo Earnings Incoming: Morgan Stanley Sees Long-Term Profit Potential​Insights – On November 21, Chinese e-commerce giant Pinduoduo (PDD) will release its Q3 2024 earnings.
Author  Mitrade
Nov 20, 2024
​Insights – On November 21, Chinese e-commerce giant Pinduoduo (PDD) will release its Q3 2024 earnings.
placeholder
Elon Musk’s xAI and Neuralink Launch New Funding Rounds​Billionaire Elon Musk recently raised funds for his two high-profile tech companies, xAI and Neuralink.
Author  Insights
Jun 03, 2025
​Billionaire Elon Musk recently raised funds for his two high-profile tech companies, xAI and Neuralink.
placeholder
Bitcoin briefly loses 2025 gains as crypto plunges over the weekend.Bitcoin experienced a sharp decline this weekend, briefly erasing its 2025 gains and dipping below its year-opening value of $93,507. The cryptocurrency fell to a low of $93,029 on Sunday, representing a 25% drop from its all-time high in October. Although it has rebounded slightly to around $94,209, the pressures on the market remain significant. The downturn occurred despite the reopening of the U.S. government on Thursday, which many had hoped would provide essential support for crypto markets. This year initially appeared promising for cryptocurrencies, particularly after the inauguration of President Donald Trump, who has established the most pro-crypto administration thus far. However, ongoing political tensions—including Trump's tariff strategies and the recent government shutdown, lasting a historic 43 days—have contributed to several rapid price pullbacks for Bitcoin throughout the year. Market dynamics are also being influenced by Bitcoin whales—investors holding large amounts of Bitcoin—who have been offloading portions of their assets, consequently stalling price rallies even as positive regulatory developments emerge. Despite these sell-offs, analysts from Glassnode argue that this behavior aligns with typical patterns seen among long-term investors during the concluding stages of bull markets, suggesting it is not indicative of a mass exodus. Notably, Bitcoin is not alone in its struggles, as Ethereum and Solana have also recorded declines of 7.95% and 28.3%, respectively, since the start of the year, while numerous altcoins have faced even steeper losses. Looking ahead, questions linger regarding the viability of the four-year cycle thesis, particularly given the increasing institutional support and regulatory frameworks now in place in the crypto landscape. Matt Hougan, chief investment officer at Bitwise, remains optimistic, suggesting a potential Bitcoin resurgence in 2026 driven by the “debasement trade” thesis and a broader trend toward increased adoption of stablecoins, tokenization, and decentralized finance. Hougan emphasized the soundness of the underlying fundamentals, pointing to a positive outlook for the sector in the longer term.
Author  Mitrade
Nov 17, 2025
Bitcoin experienced a sharp decline this weekend, briefly erasing its 2025 gains and dipping below its year-opening value of $93,507. The cryptocurrency fell to a low of $93,029 on Sunday, representing a 25% drop from its all-time high in October. Although it has rebounded slightly to around $94,209, the pressures on the market remain significant. The downturn occurred despite the reopening of the U.S. government on Thursday, which many had hoped would provide essential support for crypto markets. This year initially appeared promising for cryptocurrencies, particularly after the inauguration of President Donald Trump, who has established the most pro-crypto administration thus far. However, ongoing political tensions—including Trump's tariff strategies and the recent government shutdown, lasting a historic 43 days—have contributed to several rapid price pullbacks for Bitcoin throughout the year. Market dynamics are also being influenced by Bitcoin whales—investors holding large amounts of Bitcoin—who have been offloading portions of their assets, consequently stalling price rallies even as positive regulatory developments emerge. Despite these sell-offs, analysts from Glassnode argue that this behavior aligns with typical patterns seen among long-term investors during the concluding stages of bull markets, suggesting it is not indicative of a mass exodus. Notably, Bitcoin is not alone in its struggles, as Ethereum and Solana have also recorded declines of 7.95% and 28.3%, respectively, since the start of the year, while numerous altcoins have faced even steeper losses. Looking ahead, questions linger regarding the viability of the four-year cycle thesis, particularly given the increasing institutional support and regulatory frameworks now in place in the crypto landscape. Matt Hougan, chief investment officer at Bitwise, remains optimistic, suggesting a potential Bitcoin resurgence in 2026 driven by the “debasement trade” thesis and a broader trend toward increased adoption of stablecoins, tokenization, and decentralized finance. Hougan emphasized the soundness of the underlying fundamentals, pointing to a positive outlook for the sector in the longer term.
placeholder
Gold declines below $4,500 on stalled US-Iran ceasefire talks, US NFP data loomsGold price (XAU/USD) edges lower to near $4,470 during the early Asian session on Friday. The precious metal remains volatile amid ongoing geopolitical turmoil. Traders will closely monitor the developments surrounding the US-Iran peace deal and the US May employment report later on Friday. 
Author  FXStreet
Jun 05, Fri
Gold price (XAU/USD) edges lower to near $4,470 during the early Asian session on Friday. The precious metal remains volatile amid ongoing geopolitical turmoil. Traders will closely monitor the developments surrounding the US-Iran peace deal and the US May employment report later on Friday. 
goTop
quote