Is Axsome Therapeutics Stock a Millionaire Maker? Here's What the Numbers Say.

Source The Motley Fool

Key Points

  • Axsome specializes in central nervous system disorders, including depression, migraine, and fibromyalgia.

  • Axsome’s Auvelity recently won approval to treat agitation associated with Alzheimer’s disease.

  • 10 stocks we like better than Axsome Therapeutics ›

Axsome Therapeutics (NASDAQ: AXSM) has been going through a particularly significant growth phase in recent years, launching drugs for central nervous system (CNS) conditions and pushing several candidates through late-stage clinical trials. Investors have recognized the company's potential and piled into the stock -- it's climbed more than 220% over the past three years.

And considering these product launches are pretty recent, and any pipeline success could produce new revenue drivers, it's fair to say this biopharma company is in the early days of its growth story. Considering this, is Axsome stock a millionaire maker? Let's take a look at what the numbers say.

Missed Nvidia in 2009? This Rare Signal Is Flashing Again. In 2009, a "Double Down" signal flashed for a little-known chipmaker called Nvidia. For the first time in years, that same "Total Conviction" signal is flashing for a company 1/100th the size of Nvidia. Continue »

An investor's hand holds out $100 bills.

Image source: Getty Images.

Three approved drugs

First, though, let's take a close look at Axsome's story as a commercial-stage company. Axsome specializes in the treatment of CNS disorders, a market that spans Alzheimer's disease, major depressive disorder, narcolepsy, fibromyalgia, and other conditions. So Axsome's capabilities open the door to many markets that could support growth over time. The company sells Auvelity for agitation linked to Alzheimer's disease, and the drug is also approved for depression. Axsome's other products are Sunosi for daytime sleepiness associated with sleep apnea or narcolepsy, and Symbravo for migraine relief.

The two most recent approvals include the Alzheimer's indication for Auvelity in April of this year and the approval of Symbravo in January of last year. So the company is in the early stages of growth in those areas -- and the potential of Axsome's drugs was evident in the latest earnings report.

Double-digit product revenue growth

Auvelity product revenue soared 59% in the quarter to $153 million, and Sunosi revenue climbed 34% to $33 million. Symbravo only launched early last year, so it doesn't have a year-over-year comparison figure -- but the company offered clues that give investors reason to be optimistic about the drug's potential. Doctors wrote about 17,000 prescriptions for the migraine drug in the first quarter, and based on the drug's growth, Axsome is increasing its Symbravo sales force.

It's also important to note that the company may still progress on payer coverage for Symbravo, which should trigger additional growth. Right now, coverage is at 57% compared to more than 80% for the company's other drugs.

Another potentially big growth driver for Axsome is the Alzheimer's indication. Auvelity was just made available to these patients in June, with a sales force of more than 600 to bring the treatment to the attention of doctors, from primary care physicians to neurologists and geriatric specialists.

Another potential launch on the horizon

Meanwhile, Axsome has submitted AXS-12 for narcolepsy to regulators for review, so another product launch may be on the horizon. And the company has solriamfetol in phase three trials for four indications: attention deficit hyperactivity disorder, major depressive disorder, binge eating disorder, and shift work disorder. Finally, AXS-14 for fibromyalgia is also in a phase 3 trial. So the company's late-stage pipeline is almost bursting at the seams, which could lead to explosive growth in the coming years if all goes smoothly.

It's clear that Axsome is a young biopharmaceutical company that's on the rise, due to recently launched drugs and candidates that are nearing the finish line. Now let's get back to our question: Could this stock make you a millionaire?

Axsome stock has climbed quite a bit in recent times, but it still could have plenty of room to run as the era of revenue growth unfolds. The company has $305 million in cash and says this position will help it fund operations "into cash flow positivity." So we really are at the start of the Axsome story.

Still, a look at the numbers shows us just how difficult it is to reach $1 million by investing in one stock. For example, if you invested $1,000 in Axsome stock and it climbed 500%, you would have $6,000. That would leave Axsome stock trading at more than $1,400 -- and at a trillion-dollar market value. That's very unlikely.

But this doesn't mean you should avoid Axsome stock. The best way to reach $1 million through investing is to buy shares of many quality companies -- and Axsome would make an excellent part of the group -- and hold on for the long term.

Should you buy stock in Axsome Therapeutics right now?

Before you buy stock in Axsome Therapeutics, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Axsome Therapeutics wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you’d have $385,055!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $1,228,089!*

Now, it’s worth noting Stock Advisor’s total average return is 902% — a market-crushing outperformance compared to 209% for the S&P 500. Don't miss the latest top 10 list, available with Stock Advisor, and join an investing community built by individual investors for individual investors.

See the 10 stocks »

*Stock Advisor returns as of July 2, 2026.

Adria Cimino has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Axsome Therapeutics. The Motley Fool has a disclosure policy.

Disclaimer: For information purposes only. Past performance is not indicative of future results.
placeholder
Gold edges higher as Fed rate cut bets undermine USD ahead of NFP dataGold (XAU/USD) edges higher during the Asian session on Friday and looks to build on the overnight bounce from the vicinity of the $3,500 psychological mark.
Author  FXStreet
Sep 05, 2025
Gold (XAU/USD) edges higher during the Asian session on Friday and looks to build on the overnight bounce from the vicinity of the $3,500 psychological mark.
placeholder
Markets in 2026: Will gold, Bitcoin, and the U.S. dollar make history again? — These are how leading institutions thinkAfter a turbulent 2025, what lies ahead for commodities, forex, and cryptocurrency markets in 2026?
Author  Insights
Dec 25, 2025
After a turbulent 2025, what lies ahead for commodities, forex, and cryptocurrency markets in 2026?
placeholder
ECB Policy Outlook for 2026: What It Could Mean for the Euro’s Next MoveWith the ECB likely holding rates steady at 2.15% and the Fed potentially extending cuts into 2026, EUR/USD may test 1.20 if Eurozone growth proves resilient, but weaker growth and an ECB pivot could pull the pair back toward 1.13 and potentially 1.10.
Author  Mitrade
Dec 26, 2025
With the ECB likely holding rates steady at 2.15% and the Fed potentially extending cuts into 2026, EUR/USD may test 1.20 if Eurozone growth proves resilient, but weaker growth and an ECB pivot could pull the pair back toward 1.13 and potentially 1.10.
placeholder
My Top 5 Stock Market Predictions for 2026Five 2026 market predictions written in a native, news-style voice: AI’s winners and losers, broader sector leadership, dividend demand, valuation cooling as the Shiller CAPE sits at 39 (Dec. 31, 2025), and quantum-computing bursts—while keeping all original facts and numbers unchanged.
Author  Mitrade
Jan 06, Tue
Five 2026 market predictions written in a native, news-style voice: AI’s winners and losers, broader sector leadership, dividend demand, valuation cooling as the Shiller CAPE sits at 39 (Dec. 31, 2025), and quantum-computing bursts—while keeping all original facts and numbers unchanged.
placeholder
Gold declines below $4,500 on stalled US-Iran ceasefire talks, US NFP data loomsGold price (XAU/USD) edges lower to near $4,470 during the early Asian session on Friday. The precious metal remains volatile amid ongoing geopolitical turmoil. Traders will closely monitor the developments surrounding the US-Iran peace deal and the US May employment report later on Friday. 
Author  FXStreet
Jun 05, Fri
Gold price (XAU/USD) edges lower to near $4,470 during the early Asian session on Friday. The precious metal remains volatile amid ongoing geopolitical turmoil. Traders will closely monitor the developments surrounding the US-Iran peace deal and the US May employment report later on Friday. 
goTop
quote