Is Iovance Biotherapeutics Stock Due for a Big Rally?

Source The Motley Fool

Key Points

  • Iovance's stock has been surging, and trading volumes have been up recently, despite no significant news.

  • The company's approved cellular therapy, Amtagvi, has the potential to become a blockbuster in the future.

  • Currently, however, the company is experiencing significant cash burn, and its losses remain high.

  • 10 stocks we like better than Iovance Biotherapeutics ›

Shares of Iovance Biotherapeutics (NASDAQ: IOVA) have been in a free fall this past year, but in recent weeks, they have experienced a bit of a surge in value. The volatile biotech stock has been picking up steam, and the share price is up roughly 67% in just the past month.

For a stock that's been struggling to gain much traction and which is still down roughly 70% over the past year, could this be the start of a much bigger rally, one that may potentially be overdue?

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A team of scientists reviewing results in a lab.

Image source: Getty Images.

Trading volumes and a price spike on no significant news

Although Iovance's stock has been rising sharply of late, there hasn't been an obvious catalyst behind the sudden movement. On July 23, trading volumes were above 110 million, which is far higher than normal (daily trading volumes are usually below 20 million for the stock).

IOVA 30-Day Average Daily Volume Chart

Data by YCharts.

Iovance didn't publish any meaningful news around the time of the spike that would have explained such a sudden surge. And its latest earnings report isn't due to come out until next week. Such movements suggest that there is a lot of speculation around the healthcare stock, which can make it a volatile holding to put in your portfolio.

Iovance has promise, but it also faces considerable risk

Unlike other biotech stocks, Iovance already has an approved treatment in its portfolio, making it a bit less risky than most. Last year, it obtained approval for Amtagvi, a cellular therapy for unresectable metastatic melanoma.

Analysts are projecting that the treatment will bring in approximately $846 million annually by 2029, and it does have the potential to be a blockbuster product, with its sales expected to reach $1 billion by the end of the decade. The challenge, however, is that in rolling out the therapy to patients, the company will continue to incur hefty costs and burn through cash. In the trailing 12 months, Iovance has used up more than $334 million just from its day-to-day operating activities. And its net loss over that time has totaled $375 million.

There's no shortage of people betting against the stock, with short interest rising significantly this year.

IOVA Percent of Float Short Chart

Data by YCharts.

Should you buy Iovance stock right now?

Iovance is a stock that shows promise. It has an approved therapy that is starting to generate sales for the business, which should make it a safer buy than many other options in biotech. And the company is also studying it for other possible indications. At a market cap of right around $1 billion, the company's valuation doesn't appear too high, and it could make for an attractive acquisition target for a larger pharma company.

While I don't think Iovance is due for a big rally, simply because there is no catalyst to explain the recent surge -- much less justify a more significant one in the weeks ahead -- it could still make for an intriguing option in the long run, given that it's in the early stages of its growth. There is risk here, but there could also be some considerable upside. Investing in Iovance may not be suitable for most, but if you have a high risk tolerance, Iovance may be worth buying today.

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David Jagielski has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Iovance Biotherapeutics. The Motley Fool has a disclosure policy.

Disclaimer: For information purposes only. Past performance is not indicative of future results.
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