Eli Lilly Stock Tumbles on Slower-Than-Expected Weight Loss Drug Sales. Is This a Buying Opportunity?

Source The Motley Fool

GLP-1 drugs have become all the rage for weight loss, with sales for drugs like Novo Nordisk's Ozempic and Eli Lilly's (NYSE: LLY) Mounjaro skyrocketing over the past year. However, Eli Lilly recently surprised investors when it cut its full-year revenue guidance ahead of an investor conference after sales of its GLP-1 drugs fell short of expectations.

Eli Lilly now expects revenue to be approximately $13.5 billion for its fourth quarter and $45 billion for the full year 2024. The company had earlier forecast full-year revenue to come in between $45.4 billion to $46 billion. Analysts, meanwhile, were projecting Q4 revenue of $13.94 billion and full-year revenue of $45.49 billion, as compiled by LSEG.

Start Your Mornings Smarter! Wake up with Breakfast news in your inbox every market day. Sign Up For Free »

The new forecast from Lilly reflects 44% year-over-year revenue growth for the fourth quarter and 32% for the year. So the company is still seeing strong growth -- just not as robust as anticipated. It is also worth noting that Lilly's original full-year revenue guidance was for $41 billion, so it handily surpassed that.

GLP-1 drugs still lead the way for Eli Lilly

Turning to its GLP-1 drugs, Lilly is looking for sales of Mounjaro to be $3.5 billion and $1.9 billion for Zepbound. Mounjaro is FDA-approved to help improve blood glucose levels in adults with type 2 diabetes, but is commonly used off-label for weight loss. Zepbound has the same active ingredient, tirzepatide, but is approved for weight loss in obese adults or overweight adults with at least one weight-related condition, such as high cholesterol or high blood pressure.

A year ago, Mounjaro had sales of $2.2 billion, so that would be an increase of 59%. Zepbound had just been introduced and only had sales of $175.8 million a year ago.

At a JPMorgan conference following the announcement, the company said the revenue shortfall stemmed from weaker-than-expected scripts for diabetes in December. The company said December is usually a strong month, as people will often get two scripts to avoid deductible costs in January, but that this did not happen this year.

Looking ahead, the company forecast 2025 revenue to come in between $58 billion to $61 billion, which would represent growth between 29% to 36%. It said it did not push its missed 2024 December sales into January, nor did it include a strong December in its 2025 guidance.

Lilly noted that it has spent aggressively to add more manufacturing capacity for its GLP-1 drugs, spending $23 billion over the last three years. It expects to be able to ship 60% more doses in the first half of 2025 compared to the first half of 2024. The company said overall capacity growth for 2025 was uncertain, as there are regulatory and technical channels it needs to work through before seeing how much capacity it can add in the back half of the year.

Meanwhile, the company discussed how its international opportunity in terms of volumes was about 9 times that of the U.S. market. However, it noted that international pricing comes in lower.

Outside its incretin drugs, the company said it saw strong performances in oncology, immunology, and neuroscience medicines. It noted that sales of non-incretin drugs rose by 20% in the quarter. It is looking for several newer non-incretin drugs to also help drive revenue in 2025, as it has several new drugs to treat conditions like cancer, ulcerative colitis, and Alzheimer's disease.

Weight loss drugs.

Image source: Getty Images.

Is it time to buy the dip on Eli Lilly?

If Lilly is correct in its assessment that its revenue shortfall was due to a lack of patients doubling scripts in December, as is typical for some drugs, the company could see a stronger-than-expected Q1. Meanwhile, its overall 2025 forecast looks to be conservative, with the company not accounting for the potential of even more doses of its popular GLP-1 drugs being available in the second half.

GLP-1 drugs are likely to remain popular, and the company has a big international opportunity ahead of it as well. Meanwhile, its non-weight loss drug portfolio is also growing nicely.

From a valuation perspective, Lilly trades at a forward price-to-earnings (P/E) of 25.4 times 2025 analyst estimates, with a price/earnings-to-growth ratio (PEG ratio) of 0.3. PEGs below 1 are generally considered undervalued, so on that basis, the stock is very cheap.

LLY PE Ratio (Forward 1y) Chart

Data by YCharts.

Given its valuation and the growth still in front of it with GLP-1 drugs, investors can look to buy the dip in Eli Lilly stock.

Should you invest $1,000 in Eli Lilly right now?

Before you buy stock in Eli Lilly, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Eli Lilly wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $818,587!*

Stock Advisor provides investors with an easy-to-follow blueprint for success, including guidance on building a portfolio, regular updates from analysts, and two new stock picks each month. The Stock Advisor service has more than quadrupled the return of S&P 500 since 2002*.

See the 10 stocks »

*Stock Advisor returns as of January 13, 2025

JPMorgan Chase is an advertising partner of Motley Fool Money. Geoffrey Seiler has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends JPMorgan Chase. The Motley Fool recommends Novo Nordisk. The Motley Fool has a disclosure policy.

Disclaimer: For information purposes only. Past performance is not indicative of future results.
placeholder
Nasdaq Index Rises for 10 Straight Days, Why Has Tesla Barely Risen?On April 14, the Nasdaq notched its tenth consecutive session of gains, marking its longest winning streak since 2023. It has risen nearly 14% from its recent lows, as the 'Magnificent Se
Author  TradingKey
8 hours ago
On April 14, the Nasdaq notched its tenth consecutive session of gains, marking its longest winning streak since 2023. It has risen nearly 14% from its recent lows, as the 'Magnificent Se
placeholder
Gold eases from four-week top as Hormuz risks temper USD weaknessGold (XAU/USD) hits a nearly four-week high during the Asian session on Wednesday, though it lacks follow-through buying and currently trades just below the $4,850 level, nearly unchanged for the day.
Author  FXStreet
11 hours ago
Gold (XAU/USD) hits a nearly four-week high during the Asian session on Wednesday, though it lacks follow-through buying and currently trades just below the $4,850 level, nearly unchanged for the day.
placeholder
Silver Price Forecasts: XAG/USD approaches $78.00 boosted by Iran peace hopesSilver (XAG/USD) is rushing higher on Tuesday, reaching fresh two-week highs right below $78.00 at the time of writing, after bouncing from lows around $72.60 on Monday.
Author  TradingKey
Yesterday 10: 01
Silver (XAG/USD) is rushing higher on Tuesday, reaching fresh two-week highs right below $78.00 at the time of writing, after bouncing from lows around $72.60 on Monday.
placeholder
Trump Blockade of Strait of Hormuz Drives Oil Price Surge, Will This Be Another TACO? On Sunday (April 13), Trump announced following the breakdown of U.S.-Iran negotiations that the U.S. Navy would impose a maritime blockade on Iranian ports starting Monday.Following the
Author  TradingKey
Apr 13, Mon
On Sunday (April 13), Trump announced following the breakdown of U.S.-Iran negotiations that the U.S. Navy would impose a maritime blockade on Iranian ports starting Monday.Following the
placeholder
U.S.-Iran Standoff in the Strait of Hormuz. Iranian-Controlled Strait Has Not Resumed Passage; Why Does Trump Still Want a Military Blockade?Following the failure of U.S.-Iran peace talks, President Trump announced on Sunday that the U.S. Navy will immediately blockade the Strait of Hormuz and prevent any vessels that have pai
Author  TradingKey
Apr 13, Mon
Following the failure of U.S.-Iran peace talks, President Trump announced on Sunday that the U.S. Navy will immediately blockade the Strait of Hormuz and prevent any vessels that have pai
goTop
quote