Eli Lilly Stock Tumbles on Slower-Than-Expected Weight Loss Drug Sales. Is This a Buying Opportunity?

Source The Motley Fool

GLP-1 drugs have become all the rage for weight loss, with sales for drugs like Novo Nordisk's Ozempic and Eli Lilly's (NYSE: LLY) Mounjaro skyrocketing over the past year. However, Eli Lilly recently surprised investors when it cut its full-year revenue guidance ahead of an investor conference after sales of its GLP-1 drugs fell short of expectations.

Eli Lilly now expects revenue to be approximately $13.5 billion for its fourth quarter and $45 billion for the full year 2024. The company had earlier forecast full-year revenue to come in between $45.4 billion to $46 billion. Analysts, meanwhile, were projecting Q4 revenue of $13.94 billion and full-year revenue of $45.49 billion, as compiled by LSEG.

Start Your Mornings Smarter! Wake up with Breakfast news in your inbox every market day. Sign Up For Free »

The new forecast from Lilly reflects 44% year-over-year revenue growth for the fourth quarter and 32% for the year. So the company is still seeing strong growth -- just not as robust as anticipated. It is also worth noting that Lilly's original full-year revenue guidance was for $41 billion, so it handily surpassed that.

GLP-1 drugs still lead the way for Eli Lilly

Turning to its GLP-1 drugs, Lilly is looking for sales of Mounjaro to be $3.5 billion and $1.9 billion for Zepbound. Mounjaro is FDA-approved to help improve blood glucose levels in adults with type 2 diabetes, but is commonly used off-label for weight loss. Zepbound has the same active ingredient, tirzepatide, but is approved for weight loss in obese adults or overweight adults with at least one weight-related condition, such as high cholesterol or high blood pressure.

A year ago, Mounjaro had sales of $2.2 billion, so that would be an increase of 59%. Zepbound had just been introduced and only had sales of $175.8 million a year ago.

At a JPMorgan conference following the announcement, the company said the revenue shortfall stemmed from weaker-than-expected scripts for diabetes in December. The company said December is usually a strong month, as people will often get two scripts to avoid deductible costs in January, but that this did not happen this year.

Looking ahead, the company forecast 2025 revenue to come in between $58 billion to $61 billion, which would represent growth between 29% to 36%. It said it did not push its missed 2024 December sales into January, nor did it include a strong December in its 2025 guidance.

Lilly noted that it has spent aggressively to add more manufacturing capacity for its GLP-1 drugs, spending $23 billion over the last three years. It expects to be able to ship 60% more doses in the first half of 2025 compared to the first half of 2024. The company said overall capacity growth for 2025 was uncertain, as there are regulatory and technical channels it needs to work through before seeing how much capacity it can add in the back half of the year.

Meanwhile, the company discussed how its international opportunity in terms of volumes was about 9 times that of the U.S. market. However, it noted that international pricing comes in lower.

Outside its incretin drugs, the company said it saw strong performances in oncology, immunology, and neuroscience medicines. It noted that sales of non-incretin drugs rose by 20% in the quarter. It is looking for several newer non-incretin drugs to also help drive revenue in 2025, as it has several new drugs to treat conditions like cancer, ulcerative colitis, and Alzheimer's disease.

Weight loss drugs.

Image source: Getty Images.

Is it time to buy the dip on Eli Lilly?

If Lilly is correct in its assessment that its revenue shortfall was due to a lack of patients doubling scripts in December, as is typical for some drugs, the company could see a stronger-than-expected Q1. Meanwhile, its overall 2025 forecast looks to be conservative, with the company not accounting for the potential of even more doses of its popular GLP-1 drugs being available in the second half.

GLP-1 drugs are likely to remain popular, and the company has a big international opportunity ahead of it as well. Meanwhile, its non-weight loss drug portfolio is also growing nicely.

From a valuation perspective, Lilly trades at a forward price-to-earnings (P/E) of 25.4 times 2025 analyst estimates, with a price/earnings-to-growth ratio (PEG ratio) of 0.3. PEGs below 1 are generally considered undervalued, so on that basis, the stock is very cheap.

LLY PE Ratio (Forward 1y) Chart

Data by YCharts.

Given its valuation and the growth still in front of it with GLP-1 drugs, investors can look to buy the dip in Eli Lilly stock.

Should you invest $1,000 in Eli Lilly right now?

Before you buy stock in Eli Lilly, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Eli Lilly wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $818,587!*

Stock Advisor provides investors with an easy-to-follow blueprint for success, including guidance on building a portfolio, regular updates from analysts, and two new stock picks each month. The Stock Advisor service has more than quadrupled the return of S&P 500 since 2002*.

See the 10 stocks »

*Stock Advisor returns as of January 13, 2025

JPMorgan Chase is an advertising partner of Motley Fool Money. Geoffrey Seiler has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends JPMorgan Chase. The Motley Fool recommends Novo Nordisk. The Motley Fool has a disclosure policy.

Disclaimer: For information purposes only. Past performance is not indicative of future results.
placeholder
Dollar holds above 100 near a 3-month high — three Fed speakers and a $69 billion auction land tonightThe dollar index closed at 100.43 on Monday, its highest close since late July, after a weekly gain of about 1% — the best in more than three months — and is holding above the 100.00 handle in Asia. Three Fed officials speak tonight alongside a $69 billion two-year note auction, the first leg of $183 billion of Treasury supply this week.
Author  Suzie
Sep 22, Tue
The dollar index closed at 100.43 on Monday, its highest close since late July, after a weekly gain of about 1% — the best in more than three months — and is holding above the 100.00 handle in Asia. Three Fed officials speak tonight alongside a $69 billion two-year note auction, the first leg of $183 billion of Treasury supply this week.
placeholder
October hike odds climb toward 60% as Goldman and BofA both flip — what Warsh's "dose of accommodation" really changedRate futures now price roughly 55% to 62% for a 25bp hike at the October 27-28 FOMC, up from about 30% before Chair Warsh's post-meeting framing that the Fed is merely "removing some accommodation." Goldman Sachs has added an October hike to its forecast and Bank of America now sees moves in both October and December. Here is the repricing, the language behind it, and the two data points that decide it.
Author  Irene Q.
Sep 23, Wed
Rate futures now price roughly 55% to 62% for a 25bp hike at the October 27-28 FOMC, up from about 30% before Chair Warsh's post-meeting framing that the Fed is merely "removing some accommodation." Goldman Sachs has added an October hike to its forecast and Bank of America now sees moves in both October and December. Here is the repricing, the language behind it, and the two data points that decide it.
placeholder
Memory chips surge, Nasdaq notches a second straight record close — why the Dow fell 185 points anywayMicron gained 5%, SanDisk 6.8%, Seagate 4% and Western Digital 3% as the memory complex led the Nasdaq Composite to a second consecutive record close of 27,244.28. But the Dow fell 185 points as JPMorgan, Wells Fargo and Schwab slid more than 3% each — a split tape that says more about positioning than about the economy.
Author  Irene Q.
Sep 23, Wed
Micron gained 5%, SanDisk 6.8%, Seagate 4% and Western Digital 3% as the memory complex led the Nasdaq Composite to a second consecutive record close of 27,244.28. But the Dow fell 185 points as JPMorgan, Wells Fargo and Schwab slid more than 3% each — a split tape that says more about positioning than about the economy.
placeholder
Gold Price Forecast: XAU/USD drifts toward $4.300 with bears gaining tractionGold (XAU/USD) retraces Tuesday’s gains on Wednesday and drifts lower, approaching the $4,300 area as the US Dollar Index (DXY) rallies further amid high US Treasury yields.
Author  FXStreet
Sep 23, Wed
Gold (XAU/USD) retraces Tuesday’s gains on Wednesday and drifts lower, approaching the $4,300 area as the US Dollar Index (DXY) rallies further amid high US Treasury yields.
placeholder
US input costs rose at the fastest pace in four years — the September flash PMI beat is an inflation story, not a growth storyUS September flash PMIs came in far above expectations, with the composite at 58.4, a five-year high. But the detail that moved markets was input cost inflation at its fastest since October 2022, driven by fuel, transport and supply shortages. Brent is back above $100 and the 10-year Treasury yield has hit its highest since 2007.
Author  Suzie
17 hours ago
US September flash PMIs came in far above expectations, with the composite at 58.4, a five-year high. But the detail that moved markets was input cost inflation at its fastest since October 2022, driven by fuel, transport and supply shortages. Brent is back above $100 and the 10-year Treasury yield has hit its highest since 2007.
goTop
quote