Novo Nordisk Trades at 10 Times Earnings While Buying Back Billions in Stock. Is This the Bottom?

Source Motley_fool

Key Points

  • Novo Nordisk is one of two leading GLP-1 producers.

  • The company is cutting prices on its GLP-1 drugs as it shifts toward a volume-driven model.

  • Wall Street is taking a "show me" approach, which could be an opportunity for long-term investors.

  • 10 stocks we like better than Novo Nordisk ›

Shares of Novo Nordisk (NYSE: NVO) have declined roughly 70% from their 2024 high. The stock is now below its level in mid-2021, when it first introduced the Wegovy GLP-1 weight-loss shot to the market. This massive decline has left Novo Nordisk trading with a price-to-earnings ratio of roughly 10x, compared to a five-year average of nearly 24x.

If you are a long-term investor, you may want to follow the company's lead and buy shares of Novo Nordisk. Here's why the future is likely to be brighter than the recent past.

Missed Nvidia in 2009? This Rare Signal Is Flashing Again. In 2009, a "Double Down" signal flashed for a little-known chipmaker called Nvidia. For the first time in years, that same "Total Conviction" signal is flashing for a company 1/100th the size of Nvidia. Continue »

A person injecting themselves with a GLP-1 drug.

Image source: Getty Images.

Novo Nordisk: Mistakes were made

Wall Street is worried about Novo Nordisk for a very good reason. Despite being the first pharmaceutical maker to bring a GLP-1 weight-loss drug to market, it quickly fell behind competitor Eli Lilly (NYSE: LLY) after it introduced its own GLP-1 drugs. There are two big problems here.

First, Eli Lilly's GLP-1 weight-loss drugs proved more effective than Novo Nordisk's. So doctors prescribed them more often. Second, Novo Nordisk struggled to keep up with demand, allowing generic competition to enter the U.S. market early. So even when Novo Nordisk's drug was in use, it didn't necessarily generate revenue for Novo Nordisk.

On the first point, the weight-loss market is huge. So there is likely to be room for more than one successful competitor. And it isn't so bad to be number two in a growing market. On the second point, Novo Nordisk appears to have learned its lesson on the supply side. That is notable today, because the drug maker was also the first to market with a pill version of a GLP-1 drug. It doesn't plan to allow generics in early this time around.

Novo Nordisk has a new focus

The pill version of its GLP-1 drug is important because it is part of a shift from selling a small amount of a high-cost drug to selling a large amount of a low-cost drug. Basically, Novo Nordisk is looking at the size of the weight-loss market and shifting to a volume-driven model. That's hurting financial results right now, but if demand is as great as expected, volume could easily offset the impact of lower prices.

That said, the healthcare sector is research-driven, and competition is fierce, but Novo Nordisk has a proven track record of innovation. In fact, it is currently working on new GLP-1 drugs, and management has high hopes for success. It could regain the lead in this emerging drug category, but being number two isn't actually all that bad. After all, PepsiCo (NASDAQ: PEP) has been second to Coca-Cola (NYSE: KO) for decades and generated plenty of profits for its shareholders.

Meanwhile, Novo Nordisk has initiated a $2.2 billion stock repurchase program. It has already begun putting that money to work, suggesting that the board of directors sees value in the shares today. Given Novo Nordisk's valuation and the fact that its share price is below its level before it began selling its GLP-1 weight-loss drugs, it seems investors may be throwing the baby out with the bathwater right now.

You need to think long-term with Novo Nordisk

The problem is that the transition to a volume-based model that Novo Nordisk has undertaken will take a little while to play out. However, given the valuation, long-term investors will likely be well rewarded if they buy this innovative drugmaker while others are fearful. Meanwhile, while you wait for a business upturn to take hold, you can focus on collecting the stock's well-above-market 4.6% yield. That yield, for reference, is supported by a solid payout ratio of 33%, which itself suggests the negative view of the business may be a bit overdone.

Should you buy stock in Novo Nordisk right now?

Before you buy stock in Novo Nordisk, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Novo Nordisk wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you’d have $334,793!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $1,257,420!*

Now, it’s worth noting Stock Advisor’s total average return is 874% — a market-crushing outperformance compared to 209% for the S&P 500. Don't miss the latest top 10 list, available with Stock Advisor, and join an investing community built by individual investors for individual investors.

See the 10 stocks »

*Stock Advisor returns as of November 1, 2026.

Reuben Gregg Brewer has positions in PepsiCo. The Motley Fool has positions in and recommends Eli Lilly and Novo Nordisk. The Motley Fool has a disclosure policy.

Disclaimer: For information purposes only. Past performance is not indicative of future results.
placeholder
Trump Bragged About Intel Stock Gains. Now the U.S. Stake Has Lost $11 BillionIntel (INTC) stock fell 29% on Friday after guiding below estimates, erasing about $11 billion from the U.S. government’s stake. The hit lands on a holding President Donald Trump has publicly credited
Author  Beincrypto
Yesterday 01: 53
Intel (INTC) stock fell 29% on Friday after guiding below estimates, erasing about $11 billion from the U.S. government’s stake. The hit lands on a holding President Donald Trump has publicly credited
placeholder
Gold Had Its Worst October Since 2008: Will It Crash Further This Week?Gold ended its worst October since the 2008 financial crisis at $3,875 an ounce on Friday. It fell 3.6% in the final session alone.When trading resumes, recent buyers are most exposed. Investors added
Author  Beincrypto
Yesterday 01: 55
Gold ended its worst October since the 2008 financial crisis at $3,875 an ounce on Friday. It fell 3.6% in the final session alone.When trading resumes, recent buyers are most exposed. Investors added
placeholder
Weekly Market Wrap: Intel’s 29% crash turned Big Tech earnings into a stock-market sell-offIntel’s 29% plunge triggered a broader sell-off in Big Tech stocks, shaking investor confidence in the tech earnings outlook. Explore this week’s key market moves, the risks facing US equities and what Australian investors should watch next.
Author  Mark Garro
Yesterday 02: 44
Intel’s 29% plunge triggered a broader sell-off in Big Tech stocks, shaking investor confidence in the tech earnings outlook. Explore this week’s key market moves, the risks facing US equities and what Australian investors should watch next.
placeholder
Bitcoin Price Outlook For November 2026: One Price Level Remains CriticalBitcoin price enters November defending $76,000, the average cost basis of short-term holders. The level was held after the Binance hack pushed BTC to a six-week low of $76,275.The shock from Binance
Author  Beincrypto
5 hours ago
Bitcoin price enters November defending $76,000, the average cost basis of short-term holders. The level was held after the Binance hack pushed BTC to a six-week low of $76,275.The shock from Binance
placeholder
Market News Today Australia: Oil Price Crashes Below $100, Gold Rebounds Above $3,900 as Nasdaq FallsOil prices plunged over 7% on US-Iran talks, gold rebounded above $3,900 and Nasdaq fell 1.07%. Explore market news ahead of the RBA decision.
Author  Mitrade Team
4 hours ago
Oil prices plunged over 7% on US-Iran talks, gold rebounded above $3,900 and Nasdaq fell 1.07%. Explore market news ahead of the RBA decision.
goTop
quote