Uniswap’s $73B Growth Fuels Optimism for DeFi and the Best Meme Coins After Leadership Change

Mary-Catherine Lader just stepped down as President and COO of Uniswap Labs after a four-year run that transformed the platform into the biggest decentralized exchange on Ethereum.

During her time at the helm, Uniswap went from scrappy startup to DeFi juggernaut, pulling in over $73B in trading volume in the last month alone. That number alone has crypto optimists buzzing.

So what’s next? Well, as Uniswap looks for its next leader, the rest of DeFi is doing what it does best – evolving fast.

New crypto projects are stepping up to fill the innovation gap and take decentralized finance to the next level.

And in true Web3 fashion, it’s not just about serious finance anymore.

Mary-Catherine Lader wasn’t just another name on the masthead. She was a driving force behind Uniswap’s rise to dominance in decentralized finance.

Joining as President and COO in 2021, she played a central role in turning Uniswap from a developer-first protocol into a fully operational, structured business.

Under her leadership, the company raised $165M in October 2022, achieving a valuation of $1.66B.

But perhaps her most impressive feat was navigating the SEC investigation that loomed over Uniswap for nearly a year.

That probe concluded in February 2025 with no enforcement action, a massive win for the entire DeFi sector.

Lader’s departure after this victory feels intentional – a well-timed baton pass now that Uniswap stands on solid ground.

It’s a clear signal: Uniswap is strong, mature, and ready for what’s next. Just like the DeFi ecosystem it helped build.

Let’s take a look at three top meme coins that could ride this next wave.

1. Best Wallet Token ($BEST) – Your DeFi Wallet Just Got Smarter

With DeFi entering a more mature phase, thanks to leaders like Mary-Catherine Lader pushing for transparency and regulation, it’s no surprise that users are demanding smarter tools.

Enter Best Wallet Token ($BEST), a next-gen crypto wallet aiming to outpace clunky legacy apps like MetaMask with advanced features, clean design, and serious security.

Right now, you can buy $BEST for just $0.025335, and the project has already pulled in a hefty $13.9M during the presale.

That’s not hype – it’s momentum. Best Wallet is packed with features that make it feel more like Apple Wallet (if Apple actually cared about DeFi).

Its standout tool? Upcoming Tokens, which lets you buy presale tokens safely and directly inside the app – no sketchy mirror sites or third-party scams.

Add to that Fireblocks-powered MPC-CMP security, reduced transaction fees, iGaming perks, and governance rights, and $BEST starts looking like a wallet token with real-world muscle.

If Uniswap’s $73B surge fuels optimism for meme coins, $BEST is where you might safely store them.

2. SUBBD Token ($SUBBD) – Turning Clout Into Crypto

The creator economy is booming, but most platforms still take a massive cut while leaving creators fighting for scraps.

SUBBD Token ($SUBBD) wants to change that by putting the power – and earnings – back into the hands of influencers, artists, and yes, even meme lords.

Built as the first AI-driven, premium content platform on the blockchain, SUBBD lets users create and monetize content with game-changing tools.

At the core is an AI agent that automates chat, edits videos, and helps creators engage fans without burning out.

And with over 250M combined followers across SUBBD’s platform, Honny brand, and ambassador network, it’s already got a massive audience primed for Web3.

Currently, you can buy $SUBBD for $0.055925, with $810K raised in presale – a strong signal of early traction. $SUBBD also offers 20% APY staking during the presale, plus real-time, low-fee crypto payments that make tipping and subscribing a breeze.

In a DeFi world shaped by leaders like Mary-Catherine Lader, who bridged traditional finance with blockchain, $SUBBD is extending that legacy – bringing AI and creator freedom to the next generation of decentralized platforms.

3. Little Pepe ($LILPEPE) – Meme Power Meets Layer‑2 Muscle

Following Uniswap’s $73B surge, DeFi’s energy isn’t confined to Ethereum alone.

Little Pepe ($LILPEPE) seizes that momentum by launching the first meme‑focused Layer‑2 blockchain built on Ethereum.

It combines the fun of meme coins with real utility, offering zero‑tax trading, lightning‑fast, low‑fee transactions, bot protection, staking, and DAO governance.

Currently, 1 $LILPEPE = $0.0015, and its presale has raised $7,2M. That funding level underscores enthusiastic backing for its vision: a Layer‑2 chain for memes.

The heart of the project is the Little Pepe Chain – EVM‑compatible, ultra‑scalable infrastructure built to launch new tokens via a meme launchpad, protect users from sniper bots, and host NFTs.

It aims for seamless edge utility for creators and traders alike, reflecting the kind of platform Uniswap’s surge inspires.

Alongside blockchain utility, it boasts a $777K giveaway, strong community traction, and plans for Tier‑1 exchange listings – that’s meme culture backed by infrastructure.

As Uniswap settles into its next chapter, Little Pepe shows how the Uniswap $73B surge fuels optimism for meme coins – fusing humor, community, and real tech into the future of DeFi.

The Torch Is Being Passed

Lader’s exit doesn’t mean DeFi is slowing down. If anything, it’s accelerating.

With projects like $BEST, $SUBBD, and $LILPEPE stepping up, the crypto world might be entering a new golden age – one that’s decentralized, community-driven, and just a little chaotic.

This article is for informational purposes only and doesn’t constitute financial advice. Always do your own research (DYOR) before investing in crypto.