Here's Why Vertex Was Willing to Pay a Premium of More Than 100% for Crinetics Pharmaceuticals

Source Motley_fool

Key Points

  • Atumelnant is a promising treatment for congenital adrenal hyperplasia that could be a key part of Vertex's future.

  • Management says it was "floored" by its results in clinical trials.

  • 10 stocks we like better than Vertex Pharmaceuticals ›

When a company acquires another business, there's often going to be a premium involved, especially if it's in good shape or has some promising assets in its portfolio. But normally, you don't see a company pay double what its current valuation is.

That's what Vertex Pharmaceuticals (NASDAQ: VRTX) recently did when it announced a $10 billion purchase of Crinetics Pharmaceuticals (NASDAQ: CRNX), a company that specializes in endocrine disorders and diseases. Vertex agreed to pay a 102% premium for the stock, slightly more than double its valuation. While it was great news for Crinetics investors, it didn't sit all that well with Vertex investors, and the stock proceeded to fall sharply on the news.

Where to invest $1,000 right now? Our analyst team just revealed what they believe are the 10 best stocks to buy right now, when you join Stock Advisor. See the stocks »

Why did Vertex pay so much for the healthcare company?

Doctor talking to a patient while making notes.

Image source: Getty Images.

Management was "floored" by this one drug

Vertex expects the assets it gets from Crinetics to add as much as $5 billion in revenue. And what really stood out to management was a particularly attractive drug: atumelnant. The drug isn't approved yet, but Vertex executives were thrilled with its progress in clinical trials as a treatment for congenital adrenal hyperplasia (CAH).

Atumelnant is a once-daily pill that has been well-tolerated in trials without serious adverse events and which helped bring patients' hormone levels back down to near normal levels. It has the potential to be a leading therapy for CAH, assuming it obtains approval.

"When we saw that data, we were floored. That is very, very important to this field."

"We are also excited by the significant potential of atumelnant to transform the treatment landscape for CAH, setting a new standard of care where patients do not have to choose between managing their excess adrenal androgens and enduring the side effects of high-dose steroids."

- Dr. Reshma Kewalramani, Vertex CEO

Vertex remains a top growth stock to own

The high price tag that Vertex paid for Crinetics stock may have alarmed investors, as shares of Vertex fell sharply on the news. Prior to the announcement on July 6, the stock was trading near its 52-week high at around $530, but would end up falling to just over $485 as of the end of last week. While it's not a huge sell-off, it does indicate that investors had a bit of initial apprehension when it was announced.

If, however, management is correct in assessing the value of the drugs it acquired and they do generate significant revenue and profit growth for Vertex, buying the stock today could prove to be a good move in the long run. Paying top dollar for quality assets can be necessary, and the good news here is that Vertex didn't have to take on debt to do the deal and is funding it via cash.

Overall, it looks like a good low-risk move for Vertex to make, reinforcing why it's an excellent growth stock to hold for the long run, as it's always looking for ways to expand.

Should you buy stock in Vertex Pharmaceuticals right now?

Before you buy stock in Vertex Pharmaceuticals, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Vertex Pharmaceuticals wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you’d have $395,679!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $1,294,805!*

Now, it’s worth noting Stock Advisor’s total average return is 929% — a market-crushing outperformance compared to 211% for the S&P 500. Don't miss the latest top 10 list, available with Stock Advisor, and join an investing community built by individual investors for individual investors.

See the 10 stocks »

*Stock Advisor returns as of July 14, 2026.

David Jagielski, CPA has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Vertex Pharmaceuticals. The Motley Fool has a disclosure policy.

Disclaimer: For information purposes only. Past performance is not indicative of future results.
placeholder
Nvidia'S stock rose ~5.39% to $207.09, bringing the market cap back to $5 trillionShares of Nvidia jumped around 5.39% to close at $207.09, bringing the chip company’s total worth back near the $5 trillion mark for the first time since geopolitical tensions sent markets tumbling earlier this year. The graphics processor manufacturer last touched this valuation level before stock prices fell during market turbulence tied to the Iran...
Author  Cryptopolitan
May 07, Thu
Shares of Nvidia jumped around 5.39% to close at $207.09, bringing the chip company’s total worth back near the $5 trillion mark for the first time since geopolitical tensions sent markets tumbling earlier this year. The graphics processor manufacturer last touched this valuation level before stock prices fell during market turbulence tied to the Iran...
placeholder
Gold Price Outlook For July 2026Gold trades near $4,140 on Tuesday, down 26% from January’s record high of $5,598 per ounce. This gold price prediction for July 2026 examines why the metal keeps falling and where it could bottom.Fiv
Author  Beincrypto
Jul 08, Wed
Gold trades near $4,140 on Tuesday, down 26% from January’s record high of $5,598 per ounce. This gold price prediction for July 2026 examines why the metal keeps falling and where it could bottom.Fiv
placeholder
Brent Crude Oil Price Jumps 11% as Trump Moves to Control Strait of HormuzThe Brent crude oil (UKOIL) price gained almost 11% on Monday, reaching $83.31 after a bounce from the $71-$73 support zone. The move ranks among the sharpest daily advances since the US-Iran conflict
Author  Beincrypto
11 hours ago
The Brent crude oil (UKOIL) price gained almost 11% on Monday, reaching $83.31 after a bounce from the $71-$73 support zone. The move ranks among the sharpest daily advances since the US-Iran conflict
placeholder
MicroStrategy Unveils Bitcoin Banking Index as Institutional Adoption Reaches 32%MicroStrategy, rebranded Strategy, has unveiled a Bitcoin Banking Adoption Index scoring how far big banks embrace Bitcoin (BTC). It puts overall institutional adoption at 32%.The index ranks 25 major
Author  Beincrypto
11 hours ago
MicroStrategy, rebranded Strategy, has unveiled a Bitcoin Banking Adoption Index scoring how far big banks embrace Bitcoin (BTC). It puts overall institutional adoption at 32%.The index ranks 25 major
placeholder
Top 5 Companies To Watch in Q3 For Stock Market TradersA record Nasdaq listing, a meme-fueled trading boom, and the largest corporate Bitcoin (BTC) holder selling its coins are set to define this quarter. These 5 companies across AI and crypto carry the s
Author  Beincrypto
11 hours ago
A record Nasdaq listing, a meme-fueled trading boom, and the largest corporate Bitcoin (BTC) holder selling its coins are set to define this quarter. These 5 companies across AI and crypto carry the s
goTop
quote