Stanley Druckenmiller Put 18% of His $3.4 Billion Portfolio in This One Stock. Is Natera a Buy?

Source Motley_fool

Key Points

  • Natera is a fast-growing healthcare diagnostics company.

  • It has a strong position in both prenatal and oncology testing.

  • Shares look expensive today, but could still be a good growth stock.

  • 10 stocks we like better than Natera ›

It can pay to track what the big investors on Wall Street are trading in quarterly 13-F filings. This quarter, legendary hedge fund manager Stanley Druckenmiller added to his largest stock position, buying more Natera (NASDAQ: NTRA) for his family office. The innovative genetic testing company now accounts for 18% of Druckenmiller's 13-F portfolio, which includes all his U.S.-listed stocks.

Should you follow Druckenmiller into Natera stock? Let's take a closer look at the numbers and find out.

Where to invest $1,000 right now? Our analyst team just revealed what they believe are the 10 best stocks to buy right now, when you join Stock Advisor. See the stocks »

Stanley Druckenmiller.

Duquesne Family Office chairman Stanley Druckenmiller. Image source: Getty Images.

Advances in DNA testing

Modern medicines and treatments have led to a growing demand for advanced patient diagnostics. To tailor medicines for patients in prenatal care or with cancer, you need to understand more about their bodies and specific genetic makeup.

Natera specializes in bridging the gap between doctors and patients, using innovative cell-free DNA testing to help diagnose outcomes. Specifically, it serves the prenatal and cancer testing markets. For pregnant patients, a doctor can use a Natera test to diagnose any problems with the fetus, all with minimal physical intervention. Its cancer testing has a variety of use cases, but an important one is checking for residual disease evidence in patients, which can be invaluable for someone dealing with cancer in remission.

This market is growing like a weed, and Natera is leading the way with its best-in-class testing innovations and patent protections. It has also recently made strides in a new pillar of its business: organ donor testing, which evaluates how well a new organ functions after transplantation.

Total revenue grew 39% year over year last quarter and is up 1,000% over the last 10 years. It is this growth inflection -- and the prospects for continued tailwinds in the sector -- that led Druckenmiller to make Natera his largest stock position.

Is Natera stock a buy?

While Natera has been a nice winner for Druckenmiller over the last few years, the stock is up almost 100% over the last 12 months, driven by solid revenue growth. Is it still a buy today?

Right now, Natera trades at an expensive-looking price-to-sales (P/S) ratio of 15, which is significantly higher than the stock market average in the United States. Investors like Druckenmiller are quite optimistic about this business's growth prospects.

We cannot value the business on earnings, since it has not generated a net profit in the last few years. However, it does have very high gross margins -- 65% last quarter -- that indicate the business will have strong bottom-line margins at greater maturity.

This means investors could earn strong long-term returns by owning Natera stock, but they should only buy if they believe this durable revenue growth will continue in the years ahead.

Should you buy stock in Natera right now?

Before you buy stock in Natera, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Natera wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you’d have $395,463!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $1,268,290!*

Now, it’s worth noting Stock Advisor’s total average return is 927% — a market-crushing outperformance compared to 211% for the S&P 500. Don't miss the latest top 10 list, available with Stock Advisor, and join an investing community built by individual investors for individual investors.

See the 10 stocks »

*Stock Advisor returns as of August 4, 2026.

Brett Schafer has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Natera. The Motley Fool has a disclosure policy.

Disclaimer: For information purposes only. Past performance is not indicative of future results.
placeholder
Whale Bets $23 Million on Gold as Deutsche Bank Sees Fair Value at $4,700A crypto whale has bet more than $23 million that gold price goes up. Deutsche Bank agrees. Its analysts put gold’s fair value near $4,700 an ounce, well above Monday’s price.The gold industry’s own r
Author  Beincrypto
15 hours ago
A crypto whale has bet more than $23 million that gold price goes up. Deutsche Bank agrees. Its analysts put gold’s fair value near $4,700 an ounce, well above Monday’s price.The gold industry’s own r
placeholder
The 80-Day XRP Price Downtrend Meets a Wall of Korean BidsXRP price is down about 2% on the day, yet it just bounced roughly 4% off its August low as South Korea keeps stacking bids under the market.The bounce is not a confirmed reversal. XRP price still tra
Author  Beincrypto
15 hours ago
XRP price is down about 2% on the day, yet it just bounced roughly 4% off its August low as South Korea keeps stacking bids under the market.The bounce is not a confirmed reversal. XRP price still tra
placeholder
Benjamin Cowen: Crypto Hasn’t Been This Cheap Since 2010, But It Might Drop LowerCrypto has not been this cheap relative to its long-term trend since 2010, according to Benjamin Cowen. Still, the Into The Cryptoverse founder warns that the bottom is not in yet.Cowen, a member of B
Author  Beincrypto
15 hours ago
Crypto has not been this cheap relative to its long-term trend since 2010, according to Benjamin Cowen. Still, the Into The Cryptoverse founder warns that the bottom is not in yet.Cowen, a member of B
placeholder
Palantir Just Crushed Wall Street by $125 Million: How Will Stock React?Palantir Technologies (PLTR) beat Wall Street on every headline figure in the second quarter and lifted its full-year outlook. Shares climbed more than 7% in after-hours trading on Monday.The data ana
Author  Beincrypto
16 hours ago
Palantir Technologies (PLTR) beat Wall Street on every headline figure in the second quarter and lifted its full-year outlook. Shares climbed more than 7% in after-hours trading on Monday.The data ana
placeholder
Is SpaceX Stock a Buy Ahead of a $104 Billion Unlock? Elon Musk AnswersElon Musk agrees that SpaceX stock is a buying opportunity. He said it in three words on X (Twitter), on the same day the stock hit an all time low.Two dates now decide who is right. Earnings land Tue
Author  Beincrypto
16 hours ago
Elon Musk agrees that SpaceX stock is a buying opportunity. He said it in three words on X (Twitter), on the same day the stock hit an all time low.Two dates now decide who is right. Earnings land Tue
goTop
quote