Why Shattuck Labs Stock Soared More Than 53% Higher This Week

Source Motley_fool

Key Points

  • The biotech published its final earnings report and business covering 2025.

  • It posted a slightly narrower-than-expected net loss for the fourth quarter.

  • 10 stocks we like better than Shattuck Labs ›

Shattuck Labs (NASDAQ: STTK) was an outlier in the healthcare sector this week, thanks mostly to a very well-received earnings report and business update. Over the five trading days, according to data compiled by S&P Global Market Intelligence, the company's shares rose by a very robust 53%.

Good news from the lab

Shattuck, a clinical-stage biotech that concentrates on developing treatments for inflammatory and immune-mediated disorders, reported its fourth quarter and full-year 2025 results on Thursday.

Will AI create the world's first trillionaire? Our team just released a report on the one little-known company, called an "Indispensable Monopoly" providing the critical technology Nvidia and Intel both need. Continue »

Two people in white lab coats looking at a computer display.

Image source: Getty Images.

As a clinical-stage company, Shattuck didn't earn any revenue in the former period. It did, however, manage to trim expenses by cutting research and development spending. All told, its loss from operations declined to under $13.4 million from $19.6 million in the fourth quarter of 2024. This filtered down into a $12.6 million ($0.12 per share) headline net loss, an improvement over the year-ago deficit of $18.7 million.

Not only was that bottom-line loss narrower, it edged past the average analyst estimate of $0.13 per share.

Shattuck also wrote that SL-325, its No. 1 developmental drug intended to treat a clutch of disorders such as Crohn's disease and ulcerative colitis, has completed enrollment in all six single-ascending dose cohorts. Full enrollment in the final, multiple-ascending dose trial should be finalized in the second quarter of this year. Management expects to divulge important data from this trial during the quarter.

In terms of its financial strength, the company wrote that the over $78 million in cash, equivalents, and short-term investments is sufficient to fund its operations into 2029.

Well-positioned for success

SL-325 is a versatile medication that could be a winner for several indications. It's little wonder that investors were cheered by the news that it's advancing nicely in its development. That $78 million-plus in Shattuck's coffers gives the company plenty of runway to properly develop the drug (and others). This is a biotech well worth watching, and certainly worth considering for a buy.

Should you buy stock in Shattuck Labs right now?

Before you buy stock in Shattuck Labs, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Shattuck Labs wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you’d have $534,817!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $1,123,912!*

Now, it’s worth noting Stock Advisor’s total average return is 964% — a market-crushing outperformance compared to 192% for the S&P 500. Don't miss the latest top 10 list, available with Stock Advisor, and join an investing community built by individual investors for individual investors.

See the 10 stocks »

*Stock Advisor returns as of March 6, 2026.

Eric Volkman has no position in any of the stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.

Disclaimer: For information purposes only. Past performance is not indicative of future results.
placeholder
Ethereum Price Prediction: What To Expect From ETH In March 2026The Ethereum price enters March after a brutal February that delivered close to 20% losses. ETH has now posted six consecutive red months starting from September 2025, a streak unprecedented in the to
Author  Beincrypto
Mar 03, Tue
The Ethereum price enters March after a brutal February that delivered close to 20% losses. ETH has now posted six consecutive red months starting from September 2025, a streak unprecedented in the to
placeholder
Bitcoin’s Second-Largest Corporate Holder Just Changed the Rules: Is MicroStrategy Next?MARA Holdings has formally rewritten its Bitcoin playbook, expanding its treasury policy to permit sales of Bitcoin held directly on its balance sheet.It raises questions about whether Strategy (Micro
Author  Beincrypto
Mar 04, Wed
MARA Holdings has formally rewritten its Bitcoin playbook, expanding its treasury policy to permit sales of Bitcoin held directly on its balance sheet.It raises questions about whether Strategy (Micro
placeholder
Is Ethereum Price’s Climb Above $2,100 a Recovery Signal or Reversal Invitation?Ethereum’s price has recently broken above the $2,100 mark, a significant move that has caught the attention of investors. Interestingly, this rise has occurred without encountering major resistance,
Author  Beincrypto
Yesterday 02: 11
Ethereum’s price has recently broken above the $2,100 mark, a significant move that has caught the attention of investors. Interestingly, this rise has occurred without encountering major resistance,
placeholder
Gold’s Price Path Beyond $6,500 Runs Through The Oil Market — Here’s WhyGold (XAU/USD) has pulled back over 7% from its all-time high near $5,590, but continues to trade above $5,160 — holding up significantly better than stock market plays and even Bitcoin in the month-o
Author  Beincrypto
Yesterday 02: 14
Gold (XAU/USD) has pulled back over 7% from its all-time high near $5,590, but continues to trade above $5,160 — holding up significantly better than stock market plays and even Bitcoin in the month-o
placeholder
Bitcoin rose about 12% after the Iran strike, while gold dippedThe global crypto market printed green following geopolitical tensions escalating in the Middle East. However, this rally managed to revive a long-running debate over a true safe-haven asset. Eric Balchunas noted that Bitcoin has climbed about 12% since the Iran strike, while gold prices have moved lower over the same period. Investors’ sentiment for digital […]
Author  Cryptopolitan
Yesterday 02: 17
The global crypto market printed green following geopolitical tensions escalating in the Middle East. However, this rally managed to revive a long-running debate over a true safe-haven asset. Eric Balchunas noted that Bitcoin has climbed about 12% since the Iran strike, while gold prices have moved lower over the same period. Investors’ sentiment for digital […]
goTop
quote