Where Will Pfizer Be in 5 Years?

Source The Motley Fool

Key Points

  • Pfizer is one of the world's largest pharmaceutical companies.

  • It has a few material patent expirations on the horizon.

  • It's doing what it has to do to deal with that headwind and others.

  • 10 stocks we like better than Pfizer ›

The 6.7% dividend yield on offer from Pfizer (NYSE: PFE) is both a sign of opportunity and risk. A lot will happen over the next five years that will determine if that dividend is sustainable. But even if it isn't, there is a material turnaround opportunity for investors if they take a risk and buy Pfizer today.

What does Pfizer do?

Pfizer is one of the largest pharmaceutical companies in the world. The drug industry is complex, and competition is fierce. Pfizer has been a long-term survivor, but that doesn't mean it hasn't gone through difficult periods. And the lofty yield is a sign that it is in the middle of a difficult period right now. It will almost certainly survive, but it isn't clear that the dividend will -- at least, not in its entirety.

Where to invest $1,000 right now? Our analyst team just revealed what they believe are the 10 best stocks to buy right now. Continue »

One of the big issues to consider here is the upcoming patent expirations for oncology drug Ibrance and cardiovascular drugs Eliquis and Vyndaqel that will occur in 2027 and 2028. Although Pfizer has a diversified drug portfolio, these are three important drugs, and the patent cliff will be a material headwind to offset.

But management is taking action. After Pfizer's drug candidate in the weight loss niche failed to pan out, it quickly inked a deal to buy Metsera (NASDAQ: MTSR) for an up-front cost of $47.50 per share in cash, or roughly $4.9 billion. There are three earnouts that could add up to $22.50 per share to that total, in what is a fairly complex deal. However, the swift action here shows that Pfizer is capable and willing to do what is necessary to keep growing its business.

In five years, the patent cliff will be in the rearview mirror. New drugs will be coming to market and hopefully growing their revenue streams. And the Metsera acquisition will be complete, assuming things go as Pfizer plans, with the company's pipeline filled with strong new drug candidates. In other words, there will be a business turnaround, which is the real reason to buy Pfizer today.

It is even dealing with the political and social headwinds that it faces. That has included an agreement to make material capital investments in the United States to avoid tariffs, and to work with the U.S. government to provide more affordable access to Pfizer's drugs. Once again, Pfizer is doing what needs to be done to ensure it not only survives, but thrives over the long term.

Doing what needs to be done could mean a dividend cut

If you have a long-term investment horizon, buying Pfizer while it is down might be a good choice for your portfolio. Notably, the shares are off of their 2021 peak by nearly 60%.

That high-water mark was likely inflated by vaccine demand during the coronavirus pandemic, which analysts extrapolated way too far into the future. And that has now left the company with a less-than-sterling image in the eyes of some investors. But the fallout from that period of exuberance is what has created today's opportunity.

And given Pfizer's long history as a business and the steps it is taking today to effect a business turnaround, it seems highly likely that it will survive. It wouldn't be surprising, in fact, to see the company thrive over the long term. There's just one caveat: You probably shouldn't buy Pfizer for the dividend, which is only paid at the discretion of the board of directors.

PFE Chart

PFE data by YCharts

The reason for this is because that last time Pfizer was in a deep funk, it cut the dividend. That 2019 decision by the board wasn't a random action; it was tied to the company's acquisition of Wyeth, for roughly $68 billion. While that was a much bigger deal than the one that was just inked for Metsera, it makes clear that the board of directors will do what's right for the company, even if that requires sacrificing the dividend.

Pfizer will be just fine in five years, but will the dividend be OK?

In five years, Pfizer will most likely be in a better position than it is today as a business. That's basically what management is working to set up right now, even as Wall Street sentiment is extremely negative.

If you are a long-term investor, both those facts combine to create a good reason to buy Pfizer today. But given the dividend history, you shouldn't buy this thinking it is a reliable dividend stock. Instead, you'll want to see the dividend as a bonus. If the dividend survives unscathed, you get a cherry on top of what is best seen as a turnaround investment.

Should you invest $1,000 in Pfizer right now?

Before you buy stock in Pfizer, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Pfizer wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you’d have $657,979!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $1,122,746!*

Now, it’s worth noting Stock Advisor’s total average return is 1,060% — a market-crushing outperformance compared to 187% for the S&P 500. Don’t miss out on the latest top 10 list, available when you join Stock Advisor.

See the 10 stocks »

*Stock Advisor returns as of October 7, 2025

Reuben Gregg Brewer has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Pfizer. The Motley Fool has a disclosure policy.

Disclaimer: For information purposes only. Past performance is not indicative of future results.
placeholder
Bitcoin Price Annual Forecast: 2025 outlook brightens on expectations of US pro-crypto policyBitcoin (BTC) price has surged more than 140% in 2024, reaching the $100K milestone in early December.
Author  FXStreet
Dec 19, 2024
Bitcoin (BTC) price has surged more than 140% in 2024, reaching the $100K milestone in early December.
placeholder
Gold Price Forecast: XAU/USD gains momentum to near $3,650, eyes on US CPI releaseThe Gold price (XAU/USD) gains momentum to near $3,645 during the early Asian session on Thursday.
Author  FXStreet
Sep 11, Thu
The Gold price (XAU/USD) gains momentum to near $3,645 during the early Asian session on Thursday.
placeholder
What to expect from Ethereum in October 2025With broader sentiment worsening, user demand falling across the Ethereum network, and institutional investors pulling back, the coin faces mounting headwinds in October.
Author  Beincrypto
Sep 30, Tue
With broader sentiment worsening, user demand falling across the Ethereum network, and institutional investors pulling back, the coin faces mounting headwinds in October.
placeholder
Bitcoin, crypto market experience largest decline in 2025 as Trump threatens fresh tariffs on ChinaBitcoin (BTC) briefly declined nearly 10% on Friday as the crypto market took a sharp downturn following US President Donald Trump's plan to raise tariffs on Chinese goods.
Author  FXStreet
Oct 11, Sat
Bitcoin (BTC) briefly declined nearly 10% on Friday as the crypto market took a sharp downturn following US President Donald Trump's plan to raise tariffs on Chinese goods.
placeholder
Gold hits fresh all-time high on US-China trade tensions and Fed rate cut betsGold (XAU/USD) attracts some follow-through buying for the second straight day and climbs to a fresh all-time peak, around the $4,059-4,060 region during the Asian session on Monday.
Author  FXStreet
10 hours ago
Gold (XAU/USD) attracts some follow-through buying for the second straight day and climbs to a fresh all-time peak, around the $4,059-4,060 region during the Asian session on Monday.
goTop
quote