Why Scholar Rock Shares Are Soaring Today

Shares of Scholar Rock Holding (NASDAQ: SRRK) are soaring today, up 13.7% as of 1:14 p.m. ET. The move comes as the S&P 500 and Nasdaq Composite were up modestly.

Scholar Rock, a biopharma company, reported positive results from a phase 2 trial of its muscle-preserving weight-loss therapy.

Where to invest $1,000 right now? Our analyst team just revealed what they believe are the 10 best stocks to buy right now. Continue »

Significant results

The study evaluated Scholar Rock's apitegromab in combination with Eli Lilly's blockbuster weight-loss drug tirzepatide (sold as Mounjaro and Zepbound). The combo showed a significant reduction in lean mass loss, a major issue with current GLP-1 treatments.

The company says that the trial showed that 30% of the weight lost by users of tirzepatide without apitegromab was lean mass, but that figure was cut in half with the addition of Scholar Rock's drug.

The company said the therapy was generally well tolerated, and that the results show it has "the potential to support healthier weight loss for millions of patients on GLP therapies by safely preserving lean mass."

Image source: Getty Images.

A massive market

GLP-1 drugs like Eli Lilly's Mounjaro and Novo Nordisk's Ozempic have been some of the most successful launches of drugs in history. The 2024 market was worth $53.5 billion and is expected to triple in size by 2030. Considering most people's desire to lose fat, not muscle, a drug like Scholar Rock's apitegromab could be massive.

With the development of any drug, nothing is guaranteed. While the results of this trial were encouraging, there is a way to go before full Food and Drug Administration approval and commercialization. I think this is a good pick, albeit one that carries some risk.

Should you invest $1,000 in Scholar Rock right now?

Before you buy stock in Scholar Rock, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Scholar Rock wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you’d have $658,297!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $883,386!*

Now, it’s worth noting Stock Advisor’s total average return is 992% — a market-crushing outperformance compared to 172% for the S&P 500. Don’t miss out on the latest top 10 list, available when you join Stock Advisor.

See the 10 stocks »

*Stock Advisor returns as of June 9, 2025

Johnny Rice has no position in any of the stocks mentioned. The Motley Fool recommends Novo Nordisk. The Motley Fool has a disclosure policy.