Why Structure Therapeutics Stock Doubled and Then Some on Monday

Source The Motley Fool

Key Points

  • Shareholders were extremely pleased by the biotech's latest news from the lab.

  • This concerned its pipeline weight-loss drug aleniglipron.

  • 10 stocks we like better than Structure Therapeutics ›

Monday was quite the day for biotech companies developing the next generation of obesity drugs. One of them, Structure Therapeutics (NASDAQ: GPCR), skyrocketed almost 103% higher in price that day on some highly promising data produced by its weight-loss candidate medication.

A successful study

Structure, which concentrates on metabolic diseases with a particular focus on obesity, unveiled the topline data for its GLP-1 drug aleniglipron. The weight-loss treatment was put through its paces in a phase 2b study.

Where to invest $1,000 right now? Our analyst team just revealed what they believe are the 10 best stocks to buy right now. Continue »

Person in a lab gazing into a microscope.

Image source: Getty Images.

Over the course of the 36-week study, Structure reported that the oral medication resulted in a placebo-adjusted average weight reduction of over 11%. By the end of the study, slightly over 10% of the participants dropped out due to adverse events.

Generally, however, aleniglipron demonstrated tolerability essentially in line with other GLP-1 obesity treatments.

Structure stated that, based on the drug's performance, the company aims to advance it into phase 3 clinical trials.

The most competitive segment

In the press release detailing the results, Structure quoted CEO Raymond Stevens as saying that aleniglipron "is differentiated and delivered clinically meaningful, competitive and dose-dependent weight loss with a safety profile appropriate for chronic use in a disease that impacts millions of people."

If it continues to perform as efficaciously and eventually wins regulatory approval, the treatment could be very competitive in a weight-loss segment that is becoming increasingly busy seemingly every day. The company will have its work cut out for it, though, as tough competitors already have obesity products on the market, and others are feverishly working to develop next-level ones.

In fact, a peer biotech, Wave Life Sciences, also announced encouraging results on Monday from a recent clinical trial of its own developmental weight-loss drug.

Should you invest $1,000 in Structure Therapeutics right now?

Before you buy stock in Structure Therapeutics, consider this:

The Motley Fool Stock Advisor analyst team just identified what they believe are the 10 best stocks for investors to buy now… and Structure Therapeutics wasn’t one of them. The 10 stocks that made the cut could produce monster returns in the coming years.

Consider when Netflix made this list on December 17, 2004... if you invested $1,000 at the time of our recommendation, you’d have $540,587!* Or when Nvidia made this list on April 15, 2005... if you invested $1,000 at the time of our recommendation, you’d have $1,118,210!*

Now, it’s worth noting Stock Advisor’s total average return is 991% — a market-crushing outperformance compared to 195% for the S&P 500. Don’t miss out on the latest top 10 list, available when you join Stock Advisor.

See the 10 stocks »

*Stock Advisor returns as of December 8, 2025

Eric Volkman has no position in any of the stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.

Disclaimer: For information purposes only. Past performance is not indicative of future results.
placeholder
Gold Price Forecast: XAU/USD flat lines near $4,200 ahead of US PCE inflation releaseGold price (XAU/USD) trades on a flat note near $4,205 during the early Asian trading hours on Friday. Rising US Treasury yields and upbeat US jobs data cap upside for the precious metal. Traders might prefer to wait on the sidelines ahead of the key US inflation data.
Author  FXStreet
Dec 05, Fri
Gold price (XAU/USD) trades on a flat note near $4,205 during the early Asian trading hours on Friday. Rising US Treasury yields and upbeat US jobs data cap upside for the precious metal. Traders might prefer to wait on the sidelines ahead of the key US inflation data.
placeholder
Bitcoin Pauses for Breath Above $92,000 as Bulls Weigh Next Run at $95,000Bitcoin consolidates above $92,000 and the 100-hour SMA as traders eye a breakout toward $96,450 or a potential retracement to $90,500 support.
Author  Mitrade
Dec 05, Fri
Bitcoin consolidates above $92,000 and the 100-hour SMA as traders eye a breakout toward $96,450 or a potential retracement to $90,500 support.
placeholder
Bitcoin Dips Below $88K as FOMC Meeting Spurs NervesBitcoin experiences significant volatility, dropping toward $87,000 ahead of a crucial Federal Reserve interest-rate decision.
Author  Mitrade
Yesterday 02: 46
Bitcoin experiences significant volatility, dropping toward $87,000 ahead of a crucial Federal Reserve interest-rate decision.
placeholder
Bitcoin Could Reach $50 Million by 2041 as Global Collateral, Says EMJ Capital’s JacksonEMJ Capital CEO Eric Jackson predicts Bitcoin could hit $50 million by 2041, arguing it will replace the Eurodollar system as the neutral collateral layer for global sovereign debt.
Author  Mitrade
18 hours ago
EMJ Capital CEO Eric Jackson predicts Bitcoin could hit $50 million by 2041, arguing it will replace the Eurodollar system as the neutral collateral layer for global sovereign debt.
placeholder
Gold Price Forecast: XAU/USD edges lower below $4,200 amid worries about hawkish Fed rate cutGold Price (XAU/USD) trades in negative territory around $4,195 during the early Asian session on Tuesday. The precious metal edges lower amid concerns that the US Federal Reserve (Fed) will adopt a hawkish tone in its rhetoric, despite delivering a rate cut on Wednesday. 
Author  FXStreet
47 mins ago
Gold Price (XAU/USD) trades in negative territory around $4,195 during the early Asian session on Tuesday. The precious metal edges lower amid concerns that the US Federal Reserve (Fed) will adopt a hawkish tone in its rhetoric, despite delivering a rate cut on Wednesday. 
goTop
quote